Bert W O'Malley Selected Research

Cytoplasmic and Nuclear Receptors (Nuclear Receptors)

1/2021	Development of improved SRC-3 inhibitors as breast cancer therapeutic agents.
4/2017	Brain nuclear receptors and body weight regulation.
7/2014	The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis.
1/2014	Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor.
4/2013	Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover.
1/2012	Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy.
12/2011	Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1.
4/2010	Global characterization of transcriptional impact of the SRC-3 coregulator.
11/2009	Nuclear receptor coregulators in cancer biology.
6/2009	Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas.

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Bert W O'Malley Research Topics

Disease

118	Neoplasms (Cancer) 10/2022 - 05/2002
41	Breast Neoplasms (Breast Cancer) 01/2021 - 11/2003
31	Squamous Cell Carcinoma of Head and Neck 12/2021 - 08/2002
21	Neoplasm Metastasis (Metastasis) 07/2021 - 03/2004
17	Head and Neck Neoplasms (Head and Neck Cancer) 01/2018 - 07/2002
15	Carcinogenesis 01/2021 - 05/2002
9	Carcinoma (Carcinomatosis) 01/2021 - 12/2007
8	Oropharyngeal Neoplasms 10/2022 - 09/2010
8	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 04/2013
7	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2020 - 09/2003
6	Body Weight (Weight, Body) 12/2019 - 09/2005
6	Endometriosis 11/2019 - 07/2012
6	Hemorrhage 01/2019 - 03/2005
5	Inflammation (Inflammations) 01/2019 - 01/2009
4	Squamous Cell Neoplasms (Squamous Cell Cancer) 10/2021 - 07/2002
4	Obesity 12/2019 - 05/2006
4	Infections 01/2019 - 03/2005
3	Weight Gain 12/2021 - 03/2005
3	Myocardial Infarction 01/2021 - 03/2005
3	Fibrosis (Cirrhosis) 12/2020 - 03/2014
3	Rhinosinusitis 01/2020 - 05/2013
3	Endometrial Neoplasms (Endometrial Cancer) 01/2018 - 12/2007
2	Wound Infection (Wound Infections) 04/2022 - 01/2016
2	Sensorineural Hearing Loss 06/2021 - 01/2018
2	Hearing Loss (Hearing Impairment) 06/2021 - 01/2018
2	Wounds and Injuries (Trauma) 01/2021 - 05/2010
2	Demyelinating Diseases (Demyelinating Disease) 01/2021 - 01/2021
2	Peripheral Nervous System Diseases (PNS Diseases) 01/2021 - 01/2021
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 10/2012
2	Thyroid Neoplasms (Thyroid Cancer) 01/2020 - 06/2007
2	Weight Loss (Weight Reduction) 01/2020 - 12/2019
2	Hypoxia (Hypoxemia) 12/2019 - 11/2019
2	Sleep Apnea Syndromes (Sleep Apnea) 11/2019 - 12/2007
2	Lung Neoplasms (Lung Cancer) 01/2019 - 05/2012
2	Ovarian Neoplasms (Ovarian Cancer) 01/2018 - 07/2009
2	Labyrinth Diseases 01/2018 - 03/2013

Drug/Important Bio-Agent (IBA)

31	Steroid Receptors (Steroid Receptor)IBA 01/2021 - 12/2002
31	Proteins (Proteins, Gene)FDA Link 01/2020 - 05/2002
17	Estrogens (Estrogen)FDA Link 01/2017 - 12/2002
16	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2021 - 12/2002
15	Hormones (Hormone)IBA 01/2021 - 03/2004
14	Estrogen ReceptorsIBA 01/2021 - 11/2005
13	Transcription Factors (Transcription Factor)IBA 01/2021 - 02/2005
11	Nuclear Receptor Coactivator 3IBA 01/2021 - 09/2005
8	Cisplatin (Platino)FDA LinkGeneric 10/2021 - 07/2002
8	Pharmaceutical PreparationsIBA 02/2021 - 08/2002
8	DNA (Deoxyribonucleic Acid)IBA 03/2016 - 02/2004
7	Interleukin-2 (IL2)IBA 03/2011 - 07/2002
6	SteroidsIBA 10/2019 - 03/2005
6	Protein Isoforms (Isoforms)IBA 01/2018 - 05/2003
6	Estrogen Receptor alphaIBA 01/2018 - 04/2005
6	Progesterone FDA LinkGeneric 01/2017 - 01/2002
6	Tamoxifen FDA LinkGeneric 11/2014 - 06/2006
5	Nuclear Receptor Coactivator 2IBA 12/2021 - 01/2012
5	Biological ProductsIBA 06/2021 - 12/2002
5	Androgen Receptors (Androgen Receptor)IBA 01/2021 - 04/2013
5	4- ethyl- 2,6- bispyridin- 3- ylmethylenecyclohexanoneIBA 01/2021 - 08/2015
5	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018 - 07/2013
5	Glucose (Dextrose)FDA LinkGeneric 04/2017 - 05/2010
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2016 - 12/2002
4	LipidsIBA 01/2021 - 03/2005
4	Matrix Metalloproteinases (MMPs)IBA 05/2012 - 04/2006
4	Messenger RNA (mRNA)IBA 04/2009 - 04/2002
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2008
3	Drug CombinationsIBA 02/2021 - 10/2019
3	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021 - 03/2004
3	ProhibitinsIBA 01/2021 - 02/2008
3	bufalinIBA 01/2018 - 03/2014
3	EnzymesIBA 01/2018 - 07/2010
3	Histones (Histone)IBA 09/2017 - 07/2014
3	Amino Acids FDA Link 10/2014 - 08/2002
3	HydrogelsIBA 03/2013 - 02/2004
3	Thymidine KinaseIBA 07/2010 - 05/2002
3	silk elastin-like protein (SELP)IBA 07/2010 - 02/2004
3	Nuclear Receptor CoactivatorsIBA 06/2010 - 06/2006
3	CarcinogensIBA 12/2007 - 05/2002
3	LactoferrinIBA 03/2007 - 09/2003
3	VaccinesIBA 01/2006 - 03/2003
3	CytokinesIBA 03/2005 - 12/2002
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 12/2021 - 12/2019
2	Citric Acid (Citrate)FDA LinkGeneric 01/2021 - 03/2015
2	PlatinumIBA 01/2020 - 07/2009
2	NexusIBA 01/2019 - 02/2010
2	ErbB Receptors (EGF Receptor)IBA 01/2019 - 01/2016
2	Small Interfering RNA (siRNA)IBA 01/2019 - 07/2014
2	Cetuximab (Erbitux)FDA Link 01/2019 - 10/2016

Therapy/Procedure

53	Therapeutics 10/2022 - 08/2002
18	Radiotherapy 10/2022 - 05/2003
16	Drug Therapy (Chemotherapy) 01/2021 - 07/2002
8	Neck Dissection (Radical Neck Dissection) 01/2021 - 12/2007
4	Free Tissue Flaps 04/2022 - 12/2007
4	Tonsillectomy 01/2021 - 12/2007
4	Length of Stay 01/2021 - 01/2008
3	Aftercare (After-Treatment) 12/2021 - 12/2014
3	Immunotherapy 07/2021 - 03/2005
3	Radiofrequency Ablation 05/2015 - 03/2011
2	Chemoradiotherapy 10/2021 - 11/2019
2	Tracheotomy 11/2019 - 12/2007
2	Stents 10/2019 - 01/2009
2	Photochemotherapy (Photodynamic Therapy) 03/2018 - 04/2016